PFI-4
Catalog No: 82406
CAS Number: 900305-37-5
Purity: 98%
PFI-4 is a potent and selective BRPF1 bromodomain inhibitor (IC50 = 80 nM). Exhibits >100-fold selectivity for BRPF1 over a panel of other bromodomains including BRPF2 (BRD1), BRPF3 and BRD4. Disrupts BRPF1 binding to histone H3.3. Cell permeable.
For research use only. We do not sell to patients.
Chemical Information
| Name | PFI-4 |
|---|---|
| Iupac Chemical Name | N-[2,3-Dihydro-1,3-dimethyl-2-oxo-6-(1-pyrrolidinyl)-1H-benzimidazol-5-yl]-2-methoxybenzamide |
| Synonyms | PFI4��PFI 4 |
| Molecular Formula | C21H24N4O3 |
| Molecular Weight | 380.44 |
| Smile | CN1C(N(C2=C1C=C(C(=C2)NC(C2=C(C=CC=C2)OC)=O)N2CCCC2)C)=O |
| InChiKey | QCIJLRJBZDBVDB-UHFFFAOYSA-N |
| InChi | InChI=1S/C21H24N4O3/c1-23-17-12-15(22-20(26)14-8-4-5-9-19(14)28-3)16(25-10-6-7-11-25)13-18(17)24(2)21(23)27/h4-5,8-9,12-13H,6-7,10-11H2,1-3H3,(H,22,26) |
| CAS Number | 900305-37-5 |
| Related CAS |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | Solid powder |
|---|---|
| Purity | 98% |
| Storage | -20 ºC for 3 years |
| Solubility | Soluble in DMSO |
| Handling | |
| Shipping Condition | Shipped under ambient temperature |
| HS Code |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
