PHA-767491, also known as CAY10572, is a potent, ATP-competitive dual cdc7/cdk9 inhibitor (IC50 values are 10 and 34 nM respectively) that prevents initiation of DNA replication.
For research use only. We do not sell to patients.
Name | PHA-767491 HCl |
---|---|
Iupac Chemical Name | 1,5,6,7-Tetrahydro-2-(4-pyridinyl)-4 H -pyrrolo[3,2- c ]pyridin-4-one hydrochloride |
Synonyms | PHA767491; PHA-767491; PHA 767491; CAY10572; CAY-10572; CAY 10572. |
Molecular Formula | C12H12ClN3O |
Molecular Weight | 249.7 |
Smile | O=C1C2=C(NC(C3=CC=NC=C3)=C2)CCN1.[H]Cl |
InChiKey | IMVNFURYBZMFDZ-UHFFFAOYSA-N |
InChi | InChI=1S/C12H11N3O.ClH/c16-12-9-7-11(8-1-4-13-5-2-8)15-10(9)3-6-14-12;/h1-2,4-5,7,15H,3,6H2,(H,14,16);1H |
CAS Number | 942425-68-5 |
Related CAS |
Packaging | Price | Availability | Purity | Shipping Time |
---|---|---|---|---|
Bulk | Enquiry | Enquiry | Enquiry |
Formulation | off-white solid |
---|---|
Purity | >98% |
Storage | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
Solubility | Soluble in DMSO |
Handling | |
Shipping Condition | Shipped under ambient temperature |
HS Code |
Targets | |
---|---|
Mechanism | |
Cell study | |
Animal study | |
Clinical study |