PIK-93 is a potent PI3K inhibitor. PIK93 selectively inhibits the type III PI 4-kinase beta enzyme, and small interfering RNA-mediated down-regulation of the individual PI 4-kinase enzymes, revealed that PI 4-kinase beta has a dominant role in ceramide transport between the ER and Golgi.
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Name | PIK-93 |
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Iupac Chemical Name | N-(5-(4-chloro-3-(N-(2-hydroxyethyl)sulfamoyl)phenyl)-4-methylthiazol-2-yl)acetamide |
Synonyms | PIK93; PIK 93; PIK-93. |
Molecular Formula | C14H16ClN3O4S2 |
Molecular Weight | 389.88 |
Smile | ClC1=C(C=C(C=C1)C1=C(N=C(S1)NC(C)=O)C)S(NCCO)(=O)=O |
InChiKey | JFVNFXCESCXMBC-UHFFFAOYSA-N |
InChi | InChI=1S/C14H16ClN3O4S2/c1-8-13(23-14(17-8)18-9(2)20)10-3-4-11(15)12(7-10)24(21,22)16-5-6-19/h3-4,7,16,19H,5-6H2,1-2H3,(H,17,18,20) |
CAS Number | 593960-11-3 |
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Packaging | Price | Availability | Purity | Shipping Time |
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Bulk | Enquiry | Enquiry | Enquiry |
Formulation | Solid powder |
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Purity | 98% by HPLC |
Storage | -20 ºC for 3 years |
Solubility | Soluble in DMSO |
Handling | |
Shipping Condition | Shipped under ambient temperature |
HS Code |
Targets | |
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Mechanism | |
Cell study | |
Animal study | |
Clinical study |