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PKC412

Catalog No: 123013
CAS Number: 120685-11-2
Purity: 98% 

PKC412 is a broad spectrum protein kinase inhibitor; inhibits conventional PKC isoforms (, , ), PDFR, VEGFR2, Syk, PKC, Flk-1, Flt3, Cdk1/B, PKA, c-Kit, c-Fgr, c-Src, VEGFR1 and EGFR. 

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Chemical Information

NamePKC412
Iupac Chemical NamePKC 412,[9S-(9S,10R,11R,13R)]-N-(2,3,10,11,12,13-Hexahydro-10-methoxy-9-methyl-1-oxo-9,13-epoxy-1H,9H-diindolo[1,2,3-gh:3',2',1'-lm]pyrrolo[3,4-j][1,7]benzodiazonin-11-yl)-N-methylbenzamide  
SynonymsCGP41231; CGP41251; Midostaurin; PKC 412; PKC-412; CGP 41231; CGP 41251 
Molecular FormulaC35H30N4O4 
Molecular Weight570.637 
SmileCC12C(C(CC(O1)N3C4=CC=CC=C4C5=C6C(=C7C8=CC=CC=C8N2C7=C53)CNC6=O)N(C)C(=O)C9=CC=CC=C9)OC
InChiKeyBMGQWWVMWDBQGC-UHFFFAOYSA-N
InChiInChI=1S/C35H30N4O4/c1-35-32(42-3)25(37(2)34(41)19-11-5-4-6-12-19)17-26(43-35)38-23-15-9-7-13-20(23)28-29-22(18-36-33(29)40)27-21-14-8-10-16-24(21)39(35)31(27)30(28)38/h4-16,25-26,32H,17-18H2,1-3H3,(H,36,40)
CAS Number120685-11-2
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Ordering Information

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FormulationSolid powder 
Purity98% 
Storage-20 ºC for 3 years 
SolubilitySoluble in DMSO 
Handling
Shipping ConditionShipped under ambient temperature 
HS Code
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Targets
Mechanism
Cell study
Animal study
Clinical study
Not available

Chemical Structure

123013 - PKC412 | CAS 120685-11-2

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