PNU-159682
Catalog No: 16071409
CAS Number: 202350-68-3
Purity: 98% by HPLC
PNU-159682 is a major active metabolite of nemorubicin (MMDX) in human liver microsomes. PNU-159682 showed > 3,000-fold cytotoxic than its parent compound(MMDX and doxorubicin). PNU-159682 interacts with DNA fragments d(CGTACG)(2), d(CGATCG)(2) and d(CGCGCG)(2) and shows a strong but reversible binding to G:C base pairs.
For research use only. We do not sell to patients.
Chemical Information
| Name | PNU-159682 |
|---|---|
| Iupac Chemical Name | (7S,9S)-6,9,11-trihydroxy-9-(2-hydroxyacetyl)-4-methoxy-7-(((1S,3R,4aS,9S,9aR,10aS)-9-methoxy-1-methyloctahydro-1H-pyrano[4',3':4,5]oxazolo[2,3-c][1,4]oxazin-3-yl)oxy)-7,9,10,12-tetrahydrotetracen-5(8H)-one |
| Synonyms | PNU-159682; PNU 159682; |
| Molecular Formula | C32H37NO12 |
| Molecular Weight | 627.643 |
| Smile | OC1=C2C(C=3C(=CC=CC3CC2=C(C=2C[C@](C[C@@H](C12)O[C@H]1C[C@H]2[C@H](O[C@@H]3[C@H](OCCN32)OC)[C@@H](O1)C)(C(CO)=O)O)O)OC)=O |
| InChiKey | NOGFHSKHNYEVCK-DQTAREDWSA-N |
| InChi | InChI=1S/C32H37NO12/c1-14-29-18(33-7-8-42-31(41-3)30(33)45-29)10-22(43-14)44-20-12-32(39,21(35)13-34)11-17-24(20)28(38)25-16(26(17)36)9-15-5-4-6-19(40-2)23(15)27(25)37/h4-6,14,18,20,22,29-31,34,36,38-39H,7-13H2,1-3H3/t14-,18-,20-,22-,29+,30+,31-,32-/m0/s1 |
| CAS Number | 202350-68-3 |
| Related CAS |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | Solid powder |
|---|---|
| Purity | 98% by HPLC |
| Storage | -20 ºC for 3 years |
| Solubility | Soluble in DMSO |
| Handling | |
| Shipping Condition | Shipped under ambient temperature |
| HS Code |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
