PQ401, a selective insulin-like growth factor-1 receptor blocker, is a novel diarylurea compound that inhibits IGF1R autophosphorylation with IC50 < 1 uM.
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Chemical Information
Name PQ401
Iupac Chemical Name 1-(5-chloro-2-methoxyphenyl)-3-(2-methylquinolin-4-yl)urea
Synonyms PQ 401; PQ-401
Molecular Formula C18H16ClN3O2
Molecular Weight 341.792
Smile CC1=NC2=CC=CC=C2C(=C1)NC(=O)NC3=C(C=CC(=C3)Cl)OC
InChiKey YBLWOZUPHDKFOT-UHFFFAOYSA-N
InChi InChI=1S/C18H16ClN3O2/c1-11-9-15(13-5-3-4-6-14(13)20-11)21-18(23)22-16-10-12(19)7-8-17(16)24-2/h3-10H,1-2H3,(H2,20,21,22,23)
CAS Number 196868-63-0
Related CAS
Ordering Information
Packaging Price Availability Purity Shipping Time
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Formulation Solid powder
Purity 98%
Storage -20 ºC for 3 years
Solubility Soluble in DMSO
Handling
Shipping Condition Shipped under ambient temperature
HS Code
Targets
Mechanism
Cell study
Animal study
Clinical study