PST3 1a
Catalog No: 24140
CAS Number: 1096144-06-7
Purity: 98% Min.
PST3 1a is a Novel selective inhibitor of the N-acetylglucosamine glycosyltransferase (MGAT5) with enzymatic activity.
For research use only. We do not sell to patients.
Chemical Information
| Name | PST3 1a |
|---|---|
| Iupac Chemical Name | 3-Hydroxy-4,5-bis-benzyloxy-6-benzyloxymethyl-2-phenyl2-oxo-2λ5-[1,2]oxaphosphinane |
| Synonyms | PST3 1a; PST3-1a; NSC-753859; NSC753859; NSC 753859 |
| Molecular Formula | C32H33O6P |
| Molecular Weight | 544.57 |
| Smile | O=P1(C2=CC=CC=C2)OC(COCC3=CC=CC=C3)C(OCC4=CC=CC=C4)C(OCC5=CC=CC=C5)C1O |
| InChiKey | BFDNKVJGHOSKET-UHFFFAOYSA-N |
| InChi | InChI=1S/C32H33O6P/c33-32-31(37-23-27-17-9-3-10-18-27)30(36-22-26-15-7-2-8-16-26)29(24-35-21-25-13-5-1-6-14-25)38-39(32,34)28-19-11-4-12-20-28/h1-20,29-33H,21-24H2 |
| CAS Number | 1096144-06-7 |
| Related CAS |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | Off-white solid |
|---|---|
| Purity | 98% Min. |
| Storage | Dry, dark and at 0 - 4℃ for short term (days to weeks) or -20℃ for long term (months to years). |
| Solubility | Soluble in DMSO |
| Handling | |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| HS Code |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
1) Zahra Hassani et. al., Phostine PST3.1a Targets MGAT5 and Inhibits Glioblastoma-Initiating Cell Invasiveness and Proliferation, Mol Cancer Res (2017) 15 (10): 1376–1387.
2) Karen Muyor et. al., MO072: PST3.1A, An Inhibitor of MGAT5 Decreases Renal Fibrosis in a Rat Model of Chronic Kidney Disease , Nephrology Dialysis Transplantation, Volume 37, Issue Supplement_3, May 2022
Chemical Structure
