Pamapimod (R-1503, Ro4402257)
Catalog No: 16122774
CAS Number: 449811-01-2
Purity: 98%
Pamapimod (R-1503, Ro4402257) is a novel, selective inhibitor of p38 mitogen-activated protein kinase. It inhibits p38 and p38 enzymatic activity with IC50 values of 0.0140.002 and 0.48 0.04 microM, respectively with no activity against p38delta or p38gamma isoforms.
For research use only. We do not sell to patients.
Chemical Information
| Name | Pamapimod (R-1503, Ro4402257) |
|---|---|
| Iupac Chemical Name | Pamapimod (R-1503, Ro4402257) |
| Synonyms | N/A |
| Molecular Formula | C19H20F2N4O4 |
| Molecular Weight | 406.38 |
| Smile | CC(C(CCO)Nc1ncc2cc(c(=O)n(c2n1)C)Oc3ccc(cc3F)F)O |
| InChiKey | RGINMGDUOJVOTG-UHFFFAOYSA-N |
| InChi | InChI=1S/C19H20F2N4O4/c1-10(27)14(5-6-26)23-19-22-9-11-7-16(18(28)25(2)17(11)24-19)29-15-4-3-12(20)8-13(15)21/h3-4,7-10,14,26-27H,5-6H2,1-2H3,(H,22,23,24) |
| CAS Number | 449811-01-2 |
| MDL | MFCD14105621 |
| Related CAS |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | crystalline solid |
|---|---|
| Purity | 98% |
| Storage | 3 years -20ºCpowder |
| Solubility | Soluble in DMSO |
| Handling | |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. |
| HS Code |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
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