Pimavanserin is an inverse agonist on the serotonin receptor subtype 5-HT2A, with 40x selectivity over 5-HT2C, and no significant affinity or activity at 5-HT2B or dopamine receptors.
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Chemical Information
Name Pimavanserin
Iupac Chemical Name 1-[(4-fluorophenyl)methyl]-1-(1-methylpiperidin-4-yl)-3-[[4-(2-methylpropoxy)phenyl]methyl]urea
Synonyms ACP-103; ACP 103; ACP103
Molecular Formula C25H34FN3O2
Molecular Weight 427.555
Smile CC(C)COC1=CC=C(C=C1)CNC(=O)N(CC2=CC=C(C=C2)F)C3CCN(CC3)C
InChiKey RKEWSXXUOLRFBX-UHFFFAOYSA-N
InChi InChI=1S/C25H34FN3O2/c1-19(2)18-31-24-10-6-20(7-11-24)16-27-25(30)29(23-12-14-28(3)15-13-23)17-21-4-8-22(26)9-5-21/h4-11,19,23H,12-18H2,1-3H3,(H,27,30)
CAS Number 706779-91-1
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Ordering Information
Packaging Price Availability Purity Shipping Time
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Formulation Solid powder
Purity 98%
Storage -20 ºC for 3 years
Solubility Soluble in DMSO
Handling
Shipping Condition Shipped under ambient temperature
HS Code
Targets
Mechanism
Cell study
Animal study
Clinical study