Ponatinib (AP24534)
Catalog No: 52107
CAS Number: 943319-70-8
Purity: 98%
Ponatinib (AP24534) is a novel, potent multi-target inhibitor of Abl, PDGFR, VEGFR2, FGFR1 and Src with IC50 of 0.37 nM, 1.1 nM, 1.5 nM, 2.2 nM and 5.4 nM, respectively
For research use only. We do not sell to patients.
Chemical Information
| Name | Ponatinib (AP24534) |
|---|---|
| Iupac Chemical Name | 3-(2-(imidazo[1,2-b]pyridazin-3-yl)ethynyl)-4-methyl-N-(4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)benzamide |
| Synonyms | N/A |
| Molecular Formula | C29H27F3N6O |
| Molecular Weight | 532.56 |
| Smile | N=1C=C(N2N=CC=CC21)C#CC=2C=C(C(=O)NC1=CC(=C(C=C1)CN1CCN(CC1)C)C(F)(F)F)C=CC2C |
| InChiKey | PHXJVRSECIGDHY-UHFFFAOYSA-N |
| InChi | InChI=1S/C29H27F3N6O/c1-20-5-6-22(16-21(20)8-10-25-18-33-27-4-3-11-34-38(25)27)28(39)35-24-9-7-23(26(17-24)29(30,31)32)19-37-14-12-36(2)13-15-37/h3-7,9,11,16-18H,12-15,19H2,1-2H3,(H,35,39) |
| CAS Number | 943319-70-8 |
| Related CAS |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Purity | 98% |
|---|---|
| Handling | |
| HS Code |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
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