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Purvalanol A

Catalog No: 52564
CAS Number: 212844-53-6
Purity: 98% 

Purvalanol A(NG-60) is a potent, cell-permeable, and selective inhibitor of cyclin-dependent kinases (CDKs) with IC50 values of 4, 70, 35, 850, and 75 nM for cdc2/cyclin B, Cdk2/cyclin A, Cdk2/cyclin E, Cdk4/cyclin D1 and Cdk5-p35, respectively. 

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Chemical Information

NamePurvalanol A
Molecular FormulaC19H25ClN6O 
Molecular Weight388.89 
SmileCC(C)[C@H](CO)Nc1nc(c2c(n1)n(cn2)C(C)C)Nc3cccc(c3)Cl
InChiKeyPMXCMJLOPOFPBT-HNNXBMFYSA-N
InChiInChI=1S/C19H25ClN6O/c1-11(2)15(9-27)23-19-24-17(22-14-7-5-6-13(20)8-14)16-18(25-19)26(10-21-16)12(3)4/h5-8,10-12,15,27H,9H2,1-4H3,(H2,22,23,24,25)/t15-/m0/s1
CAS Number212844-53-6
MDLMFCD02179211
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Purity98% 
Handling
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Coming soon.
Targets
Mechanism
Cell study
Animal study
Clinical study
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Chemical Structure

52564 - Purvalanol A | CAS 212844-53-6

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