QNZ46 is a noncompetitive and voltage-independent antagonist selective for NR2C/D containing NMDA receptors (IC50= 6, 3, 229, and >300 M for NR2C, NR2D, NR2A, and NR2B, respectively). Inhibition on NR2C/D containing NMDA receptors is glutamate-binding, but not glycine-binding, dependent.
For research use only. We do not sell to patients.