Quizartinib
Catalog No: 82703
CAS Number: 950769-58-1
Purity: 98%
Quizartinib is a second-generation FLT3 inhibitor for Flt3(ITD/WT) with IC50 of 1.1 nM/4.2 nM, 10-fold more selective for Flt3 than KIT, PDGFR_alpha_, PDGFR_beta_, RET, and CSF-1R.
For research use only. We do not sell to patients.
Chemical Information
| Name | Quizartinib |
|---|---|
| Iupac Chemical Name | N-(5-tert-butyl-isoxazol-3-yl)-N'-{4-[7-(2-morpholin-4-yl-ethoxy)imidazo[2,1-b][1,3]benzothiazol-2-yl]phenyl}urea dihydrochloride |
| Synonyms | AC-220; AC220 |
| Molecular Formula | C29H32N6O4S |
| Molecular Weight | 560.67 |
| Smile | Cl.Cl.C(C)(C)(C)C1=CC(=NO1)NC(=O)NC1=CC=C(C=C1)C=1N=C2SC3=C(N2C1)C=CC(=C3)OCCN3CCOCC3 |
| InChiKey | DHYPGRVMIOATAE-UHFFFAOYSA-N |
| InChi | InChI=1S/C29H32N6O4S.2ClH/c1-29(2,3)25-17-26(33-39-25)32-27(36)30-20-6-4-19(5-7-20)22-18-35-23-9-8-21(16-24(23)40-28(35)31-22)38-15-12-34-10-13-37-14-11-34;;/h4-9,16-18H,10-15H2,1-3H3,(H2,30,32,33,36);2*1H |
| CAS Number | 950769-58-1 |
| Related CAS |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | Solid powder |
|---|---|
| Purity | 98% |
| Storage | -20 ºC for 3 years |
| Solubility | Soluble in DMSO |
| Handling | |
| Shipping Condition | Shipped under ambient temperature |
| HS Code |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
