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RU-SKI 43

Catalog No: 6111503
CAS Number: 1043797-53-0
Purity: 98% 

RU-SKI 43 is a small molecule inhibitor of Hhat(Hedgehog acyltransferase), the enzyme responsible for the attachment of palmitate onto Shh.


RU-SKI 43 reduced pancreatic cancer cell proliferation and Gli-1 activation through Smoothened-independent non-canonical signaling. In addition, RU-SKI 43 treatment inhibited two key proliferative pathways regulated by Akt and mTOR.


 

For research use only. We do not sell to patients.

Chemical Information

NameRU-SKI 43
Iupac Chemical NameRU-SKI 43 
SynonymsRU-SKI43; Hhat Inhibitor 
Molecular FormulaC22H30N2O2S 
Molecular Weight386.55 
InChiKey
InChi
CAS Number1043797-53-0
Related CAS

Ordering Information

PackagingPriceAvailabilityPurityShipping Time
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Formulationcrystalline solid 
Purity98% 
Storage3 years -20ºCpowder 
SolubilitySoluble in DMSO 
Handling
Shipping ConditionShipped under ambient temperature as non-hazardous chemical. 
HS Code
Coming soon.
Targets
Mechanism
Cell study
Animal study
Clinical study
Not available

Chemical Structure

6111503 - RU-SKI 43 | CAS 1043797-53-0

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