Rbin-1(ribozinoindole-1) is a potent chemical inhibitor of eukaryotic ribosome assembly. It inhibits recombinant full-length Mdn1's ATPase activity in vitro.
Ribozinoindoles are potent chemical inhibitors of eukaryotic ribosome assembly. Rbin-1 targets Mdn1 or cellular processes that involve this protein. It efficiently inhibit the growth of yeast cells.
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Name | Rbin-1 |
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Iupac Chemical Name | 3-((2-methylallyl)thio)-5H-[1,2,4]triazino[5,6-b]indole |
Synonyms | ribozinoindole-1 |
Molecular Formula | C13H12N4S |
Molecular Weight | 256.33 |
Smile | C=C(C)CSC1=NN=C2C(NC3=C2C=CC=C3)=N1 |
InChiKey | LPCWHNSRTRBKBO-UHFFFAOYSA-N |
InChi | InChI=1S/C13H12N4S/c1-8(2)7-18-13-15-12-11(16-17-13)9-5-3-4-6-10(9)14-12/h3-6H,1,7H2,2H3,(H,14,15,17) |
CAS Number | 328023-11-6 |
Related CAS |
Packaging | Price | Availability | Purity | Shipping Time |
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Formulation | crystalline solid |
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Purity | 98% |
Storage | 3 years -20ºCpowder |
Solubility | Soluble in DMSO |
Handling | |
Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. |
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Mechanism | |
Cell study | |
Animal study | |
Clinical study |