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Regorafenib

Catalog No: 52722
CAS Number: 755037-03-7
Purity: 98% 

Regorafenib (BAY 73-4506) is a multi-target inhibitor for VEGFR1, VEGFR2, VEGFR3, PDGFR, Kit, RET and Raf-1 with IC50 of 13 nM/4.2 nM/46 nM, 22 nM, 7 nM, 1.5 nM and 2.5 nM, respectively. 

For research use only. We do not sell to patients.

Chemical Information

NameRegorafenib
Molecular FormulaC21H15ClF4N4O3 
Molecular Weight482.82 
SmileCNC(=O)c1cc(ccn1)Oc2ccc(c(c2)F)NC(=O)Nc3ccc(c(c3)C(F)(F)F)Cl
InChiKeyFNHKPVJBJVTLMP-UHFFFAOYSA-N
InChiInChI=1S/C21H15ClF4N4O3/c1-27-19(31)18-10-13(6-7-28-18)33-12-3-5-17(16(23)9-12)30-20(32)29-11-2-4-15(22)14(8-11)21(24,25)26/h2-10H,1H3,(H,27,31)(H2,29,30,32)
CAS Number755037-03-7
MDLMFCD16038047
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Ordering Information

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Purity98% 
SolubilityDMSO ��95mg/mL Water <1.2mg/mL Ethanol ��7.6mg/mL 
Handling
HS Code
Coming soon.
Targets
Mechanism
Cell study
Animal study
Clinical study
Not available

Chemical Structure

52722 - Regorafenib | CAS 755037-03-7

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