Ribociclib (LEE011) is an orally available, and highly specific CDK4/6 inhibitor. Phase 3
For research use only. We do not sell to patients.
Name | Ribociclib (LEE011) |
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Iupac Chemical Name | 7-cyclopentyl-N,N-dimethyl-2-((5-(piperazin-1-yl)pyridin-2-yl)amino)-7H-pyrrolo[2,3-d]pyrimidine-6-carboxamide |
Synonyms | Ribociclib;LEE011 |
Molecular Formula | C23H30N8O |
Molecular Weight | 434.54 |
Smile | C1(CCCC1)N1C(=CC2=C1N=C(N=C2)NC2=NC=C(C=C2)N2CCNCC2)C(=O)N(C)C |
InChiKey | RHXHGRAEPCAFML-UHFFFAOYSA-N |
InChi | InChI=1S/C23H30N8O/c1-29(2)22(32)19-13-16-14-26-23(28-21(16)31(19)17-5-3-4-6-17)27-20-8-7-18(15-25-20)30-11-9-24-10-12-30/h7-8,13-15,17,24H,3-6,9-12H2,1-2H3,(H,25,26,27,28) |
CAS Number | 1211441-98-3 |
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Packaging | Price | Availability | Purity | Shipping Time |
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Formulation | yellow solid |
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Purity | 98% |
Storage | 3 years -20ºCpowder 6 months-80ºCin solvent |
Solubility | 5mg/ml in DMSO |
Handling | |
Shipping Condition | Shipped under ambient temperature |
HS Code |
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Mechanism | |
Cell study | |
Animal study | |
Clinical study |