Rocilinostat (ACY-1215)
Catalog No: 52104
CAS Number: 1316214-52-4
Purity: 98%
Rocilinostat (ACY-1215) is a selective HDAC6 inhibitor with IC50 of 5 nM. It is >10-fold more selective for HDAC6 than HDAC1/2/3 (class I HDACs) with slight activity against HDAC8, minimal activity against HDAC4/5/7/9/11, Sirtuin1, and Sirtuin2. Phase 2.
For research use only. We do not sell to patients.
Chemical Information
| Name | Rocilinostat (ACY-1215) |
|---|---|
| Iupac Chemical Name | 5-Pyrimidinecarboxamide, 2-(diphenylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]- |
| Synonyms | Rocilinostat,ACY-1215 |
| Molecular Formula | C24H27N5O3 |
| Molecular Weight | 433.5 |
| Smile | C1(=CC=CC=C1)N(C1=NC=C(C=N1)C(=O)NCCCCCCC(=O)NO)C1=CC=CC=C1 |
| InChiKey | QGZYDVAGYRLSKP-UHFFFAOYSA-N |
| InChi | InChI=1S/C24H27N5O3/c30-22(28-32)15-9-1-2-10-16-25-23(31)19-17-26-24(27-18-19)29(20-11-5-3-6-12-20)21-13-7-4-8-14-21/h3-8,11-14,17-18,32H,1-2,9-10,15-16H2,(H,25,31)(H,28,30) |
| CAS Number | 1316214-52-4 |
| Related CAS |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Purity | 98% |
|---|---|
| Storage | 3 years -20ºCpowder |
| Solubility | 5mg/ml in DMSO |
| Handling | |
| Shipping Condition | Shipped under ambient temperature |
| HS Code |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
-cas-1316214-52-4.png)