Rucaparib(AG-014699,PF-01367338)
Catalog No: 52009
CAS Number: 459868-92-9
Purity: 98%
Rucaparib (AG-014699, PF-01367338) is an inhibitor of PARP with Ki of 1.4 nM for PARP1, also showing binding affinity to eight other PARP domains. Phase 3.
For research use only. We do not sell to patients.
Chemical Information
| Name | Rucaparib(AG-014699,PF-01367338) |
|---|---|
| Iupac Chemical Name | 8-fluoro-2-(4-((methylamino)methyl)phenyl)-4,5-dihydro-2aH-azepino[5,4,3-cd]indol-6(3H)-one phosphate |
| Synonyms | AG-14447,AG-014447,AG-14699,PF-01367338 |
| Molecular Formula | C19H18FN3O.H3PO4 |
| Molecular Weight | 421.36 |
| Smile | P(=O)(O)(O)O.FC=1C=C2C=3C(C(=NC3C1)C1=CC=C(C=C1)CNC)CCNC2=O |
| InChiKey | QATCNHOHGCRVDI-UHFFFAOYSA-N |
| InChi | InChI=1S/C19H18FN3O.H3O4P/c1-21-10-11-2-4-12(5-3-11)18-14-6-7-22-19(24)15-8-13(20)9-16(23-18)17(14)15;1-5(2,3)4/h2-5,8-9,14,21H,6-7,10H2,1H3,(H,22,24);(H3,1,2,3,4) |
| CAS Number | 459868-92-9 |
| Related CAS |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | yellow solid |
|---|---|
| Purity | 98% |
| Storage | 3 years -20ºCpowder 6 months-80ºCin solvent |
| Solubility | 2mg/ml in DMSO |
| Handling | |
| HS Code |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
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