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SAR-405

Catalog No: 2017882
CAS Number: 1523406-39-4
Purity: 98.0% 

<span style="color:#34495E;font-family:" font-size:14px;background-color:#ffffff;">SAR-405 is a potent and selective PIK3C3/Vps34 inhibitor that prevents autophagy and synergizes with MTOR inhibition in tumor cells. 

For research use only. We do not sell to patients.

Chemical Information

NameSAR-405
Iupac Chemical Name(S)-9-((5-chloropyridin-3-yl)methyl)-2-((R)-3-methylmorpholino)-8-(trifluoromethyl)-6,7,8,9-tetrahydro-4H-pyrimido[1,2-a]pyrimidin-4-one 
SynonymsSAR-405;SAR 405;SAR405 
Molecular FormulaC19H21ClF3N5O2 
Molecular Weight443.8552 
SmileClC=1C=C(C=NC1)CN1[C@@H](CCN2C1=NC(=CC2=O)N2[C@@H](COCC2)C)C(F)(F)F
InChiKeySPDQRCUBFSRAFI-DOMZBBRYSA-N
InChiInChI=1S/C19H21ClF3N5O2/c1-12-11-30-5-4-26(12)16-7-17(29)27-3-2-15(19(21,22)23)28(18(27)25-16)10-13-6-14(20)9-24-8-13/h6-9,12,15H,2-5,10-11H2,1H3/t12-,15+/m1/s1
CAS Number1523406-39-4
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Ordering Information

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Formulationoff-white solid 
Purity98.0% 
Storage-20 ºC for 3 years 
SolubilitySoluble in DMSO 
Handling
Shipping ConditionShipped under ambient temperature 
HS Code
Coming soon.
Targets
Mechanism
Cell study
Animal study
Clinical study
Not available

Chemical Structure

2017882 - SAR-405 | CAS 1523406-39-4

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