SAR260301是强有力的和选择性组 I 磷脂酰肌醇-3-激酶(PI3K)β特定抑制剂的同种型,IC50值为52 nM。
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Name | SAR260301 |
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Iupac Chemical Name | (S)-2-(2-(2-methylindolin-1-yl)-2-oxoethyl)-6-morpholinopyrimidin-4(3H)-one |
Synonyms | SAR260301; SAR260301; SAR 260301. |
Molecular Formula | C19H22N4O3 |
Molecular Weight | 354.40298 |
Smile | O=C1NC(CC(N2[C@@H](C)CC3=C2C=CC=C3)=O)=NC(N4CCOCC4)=C1 |
InChiKey | UAXHPOBBKRWJGA-ZDUSSCGKSA-N |
InChi | InChI=1S/C19H22N4O3/c1-13-10-14-4-2-3-5-15(14)23(13)19(25)11-16-20-17(12-18(24)21-16)22-6-8-26-9-7-22/h2-5,12-13H,6-11H2,1H3,(H,20,21,24)/t13-/m0/s1 |
CAS Number | 1260612-13-2 |
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Packaging | Price | Availability | Purity | Shipping Time |
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Bulk | Enquiry | Enquiry | Enquiry |
Formulation | 类白色至白色固体 |
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Purity | >98% |
Storage | 短期可在0-4度保存,数天至数月;长期可在-20度保存三年。 |
Solubility | 可溶于DMSO |
Handling | |
Shipping Condition | 可在常温下运输 |
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Mechanism | |
Cell study | |
Animal study | |
Clinical study |