1: Davies SP, Reddy H, Caivano M, Cohen P. Specificity and mechanism of action of some commonly used protein kinase inhibitors. Biochem J. 2000 Oct 1;351(Pt 1):95-105. doi: 10.1042/0264-6021:3510095. PMID: 10998351; PMCID: PMC1221339.
2: Shanware NP, Williams LM, Bowler MJ, Tibbetts RS. Non-specific in vivo inhibition of CK1 by the pyridinyl imidazole p38 inhibitors SB 203580 and SB 202190. BMB Rep. 2009 Mar 31;42(3):142-7. doi: 10.5483/bmbrep.2009.42.3.142. PMID: 19336000; PMCID: PMC4412876.
3: Glover M, Sweeny C, Davis B, O'Shaughnessy KM. A Single Amino Acid Substitution Makes WNK4 Susceptible to SB 203580 and SB 202190. Open Med Chem J. 2010 Sep 3;4:57-61. doi: 10.2174/1874104501004010057. PMID: 21249167; PMCID: PMC3023092.
4: Nassar K, Tura A, Lüke J, Lüke M, Grisanti S, Grisanti S. A p38 MAPK inhibitor improves outcome after glaucoma filtration surgery. J Glaucoma. 2015 Feb;24(2):165-78. doi: 10.1097/IJG.0000000000000201. PMID: 25493622.
5: Liao Y, Weng J, Chen L, Hu N, Yuan X, Wang J, He F, Cai Y, Huang Q, Wang J, Huang L. Comprehensive analysis of SLC43A2 on the tumor immune microenvironment and prognosis of liver hepatocellular carcinoma. Front Genet. 2022 Sep 16;13:911378. doi: 10.3389/fgene.2022.911378. PMID: 36186480; PMCID: PMC9523210.
6: Vilar S, Quezada E, Uriarte E, Costanzi S, Borges F, Viña D, Hripcsak G. Computational Drug Target Screening through Protein Interaction Profiles. Sci Rep. 2016 Nov 15;6:36969. doi: 10.1038/srep36969. PMID: 27845365; PMCID: PMC5109486.
7: Michel AD, Thompson KM, Simon J, Boyfield I, Fonfria E, Humphrey PP. Species and response dependent differences in the effects of MAPK inhibitors on P2X(7) receptor function. Br J Pharmacol. 2006 Dec;149(7):948-57. doi: 10.1038/sj.bjp.0706938. Epub 2006 Oct 9. PMID: 17031382; PMCID: PMC2014687.
8: Velmurugan S, Liu T, Chen KC, Despa F, O'Rourke B, Despa S. Distinct Effects of Mitochondrial Na+/Ca2+ Exchanger Inhibition and Ca2+ Uniporter Activation on Ca2+ Sparks and Arrhythmogenesis in Diabetic Rats. J Am Heart Assoc. 2023 Jul 18;12(14):e029997. doi: 10.1161/JAHA.123.029997. Epub 2023 Jul 8. PMID: 37421267; PMCID: PMC10382117.
9: Faustino RS, Cheung P, Richard MN, Dibrov E, Kneesch AL, Deniset JF, Chahine MN, Lee K, Blackwood D, Pierce GN. Ceramide regulation of nuclear protein import. J Lipid Res. 2008 Mar;49(3):654-62. doi: 10.1194/jlr.M700464-JLR200. Epub 2007 Dec 14. PMID: 18083977.
10: Zhang Z, Song Z, Luo L, Zhu Z, Zuo X, Ju C, Wang X, Ma Y, Wu T, Yao Z, Zhou J, Chen B, Ding T, Wang Z, Hu X. Photobiomodulation inhibits the expression of chondroitin sulfate proteoglycans after spinal cord injury via the Sox9 pathway. Neural Regen Res. 2024 Jan;19(1):180-189. doi: 10.4103/1673-5374.374136. PMID: 37488865; PMCID: PMC10479858.
11: Feng S, Daw JN, Chen QM. Histone deacetylase inhibitors prevent H2O2 from inducing stress granule formation. Curr Res Toxicol. 2020 Oct 31;1:141-148. doi: 10.1016/j.crtox.2020.10.004. PMID: 34345843; PMCID: PMC8320627.
12: Cheng X, Ni B, Zhang F, Hu Y, Zhao J. High Glucose-Induced Oxidative Stress Mediates Apoptosis and Extracellular Matrix Metabolic Imbalances Possibly via p38 MAPK Activation in Rat Nucleus Pulposus Cells. J Diabetes Res. 2016;2016:3765173. doi: 10.1155/2016/3765173. Epub 2016 Aug 22. PMID: 27635402; PMCID: PMC5011214.
13: Börgeling Y, Schmolke M, Viemann D, Nordhoff C, Roth J, Ludwig S. Inhibition of p38 mitogen-activated protein kinase impairs influenza virus-induced primary and secondary host gene responses and protects mice from lethal H5N1 infection. J Biol Chem. 2014 Jan 3;289(1):13-27. doi: 10.1074/jbc.M113.469239. Epub 2013 Nov 4. PMID: 24189062; PMCID: PMC3879537.
14: Espejo MS, Aiello I, Sepúlveda M, Vila Petroff MG, Aiello EA, De Giusti VC. The reduced myofilament responsiveness to calcium contributes to the negative force-frequency relationship in rat cardiomyocytes: role of reactive oxygen species and p-38 map kinase. Pflugers Arch. 2017 Dec;469(12):1663-1673. doi: 10.1007/s00424-017-2058-z. Epub 2017 Aug 23. PMID: 28836001.
15: Tang C, Wang M, Liu J, Zhang C, Li L, Wu Y, Chu Y, Wu D, Liu H, Yuan X. A Cyclopentanone Compound Attenuates the Over-Accumulation of Extracellular Matrix and Fibrosis in Diabetic Nephropathy via Downregulating the TGF-β/p38MAPK Axis. Biomedicines. 2022 Dec 16;10(12):3270. doi: 10.3390/biomedicines10123270. PMID: 36552026; PMCID: PMC9775671.
16: Lv C, Sun L, Guo Z, Li H, Kong D, Xu B, Lin L, Liu T, Guo D, Zhou J, Li Y. Circular RNA regulatory network reveals cell-cell crosstalk in acute myeloid leukemia extramedullary infiltration. J Transl Med. 2018 Dec 17;16(1):361. doi: 10.1186/s12967-018-1726-x. PMID: 30558617; PMCID: PMC6297994.
17: Gahring LC, Osborne-Hereford AV, Vasquez-Opazo GA, Rogers SW. Tumor necrosis factor alpha enhances nicotinic receptor up-regulation via a p38MAPK-dependent pathway. J Biol Chem. 2008 Jan 11;283(2):693-9. doi: 10.1074/jbc.M707330200. Epub 2007 Oct 31. PMID: 17977823.
18: Yeste-Velasco M, Folch J, Pallàs M, Camins A. The p38(MAPK) signaling pathway regulates neuronal apoptosis through the phosphorylation of the retinoblastoma protein. Neurochem Int. 2009 Feb;54(2):99-105. doi: 10.1016/j.neuint.2008.10.004. Epub 2008 Oct 21. PMID: 19007833.
19: Kühn K, Lotz M. Mechanisms of sodium nitroprusside-induced death in human chondrocytes. Rheumatol Int. 2003 Sep;23(5):241-7. doi: 10.1007/s00296-003-0299-y. Epub 2003 Mar 18. PMID: 14504917.
20: Mailem RC, Tayo LL. Drug Repurposing Using Gene Co-Expression and Module Preservation Analysis in Acute Respiratory Distress Syndrome (ARDS), Systemic Inflammatory Response Syndrome (SIRS), Sepsis, and COVID-19. Biology (Basel). 2022 Dec 15;11(12):1827. doi: 10.3390/biology11121827. PMID: 36552336; PMCID: PMC9775208.
