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SB-590885

Catalog No: 101208
CAS Number: 405554-55-4
Purity: 98% 

SB590885 is a potent B-Raf inhibitor with Ki of 0.16 nM, 11-fold greater selectivity for B-Raf over c-Raf, no inhibition to other human kinases. 

For research use only. We do not sell to patients.

Chemical Information

NameSB-590885
Iupac Chemical Name5-[2-[4-[2-(Dimethylamino)ethoxy]phenyl]-5-(4-pyridinyl)-1H-imidazol-4-yl]-2,3-dihydro-1H-inden-1-one oxime; 5-[2-[4-[2-(DIMETHYLAMINO)ETHOXY]PHENYL]-5-(4-PYRIDINYL)-1H-IMIDAZOL-4-YL]-2,3-DIHYDRO-1H-INDEN-1-ON 
SynonymsSB590885; SB 590885 
Molecular FormulaC27H27N5O2 
Molecular Weight453.536 
SmileCN(CCOC1=CC=C(C=C1)C=1NC(=C(N1)C=1C=C2CCC(C2=CC1)=O)C1=CC=NC=C1)C.CN(CCOC1=CC=C(C=C1)C=1NC(=C(N1)C=1C=C2CCC(C2=CC1)=NO)C1=CC=NC=C1)C
InChiKeyZZZJCWLZDPXFDF-UHFFFAOYSA-N
InChiInChI=1S/C27H27N5O2.C27H26N4O2/c1-32(2)15-16-34-22-7-3-19(4-8-22)27-29-25(18-11-13-28-14-12-18)26(30-27)21-5-9-23-20(17-21)6-10-24(23)31-33;1-31(2)15-16-33-22-7-3-19(4-8-22)27-29-25(18-11-13-28-14-12-18)26(30-27)21-5-9-23-20(17-21)6-10-24(23)32/h3-5,7-9,11-14,17,33H,6,10,15-16H2,1-2H3,(H,29,30);3-5,7-9,11-14,17H,6,10,15-16H2,1-2H3,(H,29,30)
CAS Number405554-55-4
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Ordering Information

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FormulationSolid powder 
Purity98% 
Storage-20 ºC for 3 years 
SolubilitySoluble in DMSO 
Handling
Shipping ConditionShipped under ambient temperature 
HS Code
Coming soon.
Targets
Mechanism
Cell study
Animal study
Clinical study
Not available

Chemical Structure

101208 - SB-590885 | CAS 405554-55-4

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