SB-674042 is potent and selective OX1R antagonist. SB-674042 binds with high affinity to OX1R and mediates intracellular calcium flux in OX1R-expressing cells.
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Name | SB-674042 |
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Iupac Chemical Name | (S)-(5-(2-fluorophenyl)-2-methylthiazol-4-yl)(2-((5-phenyl-1,3,4-oxadiazol-2-yl)methyl)pyrrolidin-1-yl)methanone |
Synonyms | SB 674042; SB-674042; SB674042. |
Molecular Formula | C24H21FN4O2S |
Molecular Weight | 448.5164 |
Smile | O=C(N1[C@H](CC2=NN=C(C3=CC=CC=C3)O2)CCC1)C4=C(C5=CC=CC=C5F)SC(C)=N4 |
InChiKey | |
InChi | |
CAS Number | 483313-22-0 |
Related CAS |
Packaging | Price | Availability | Purity | Shipping Time |
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Bulk | Enquiry | Enquiry | Enquiry |
Formulation | Off-white solid to white solid |
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Purity | >98% |
Storage | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
Solubility | Soluble in DMSO |
Handling | |
Shipping Condition | Shipped under ambient temperature |
HS Code |
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Mechanism | |
Cell study | |
Animal study | |
Clinical study |