SCR7 pyrazine is a small molecule inhibitor of DNA ligase IV that prevents nonhomologous end-joining by interfering with ligase binding and activating apoptosis.
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Name | SCR7 pyrazine |
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Iupac Chemical Name | 2,3-dihydro-6,7-diphenyl-2-thioxo-4(1H)-pteridinone |
Synonyms | 6,7-diphenyl-2-sulfanylidene-1H-pteridin-4-one;2,3-Dihydro-6,7-diphenyl-2-thioxo-4(1H)-pteridinone;6,7-Diphenyl-2-thiolumazine;SCR7 pyrazine;6,7-Diphenyl-2-sulfanylpteridin-4-ol |
Molecular Formula | C18H12N4OS |
Molecular Weight | 332.4 |
Smile | O=C(C1=NC(C2=CC=CC=C2)=C(C3=CC=CC=C3)NC1=N4)NC4=S |
InChiKey | GSRTWXVBHGOUBU-UHFFFAOYSA-N |
InChi | InChI=1S/C18H12N4OS/c23-17-15-16(21-18(24)22-17)20-14(12-9-5-2-6-10-12)13(19-15)11-7-3-1-4-8-11/h1-10H,(H2,20,21,22,23,24) |
CAS Number | 14892-97-8 |
Related CAS |
Packaging | Price | Availability | Purity | Shipping Time |
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Formulation | light-yellow solid |
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Purity | >98% |
Storage | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
Solubility | Soluble in DMSO |
Handling | |
Shipping Condition | Shipped under ambient temperature |
HS Code |
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Mechanism | |
Cell study | |
Animal study | |
Clinical study |