SD-208 is a potent, orally active ATP-competitive transforming growth factor- receptor 1 (TGF-RI) inhibitor (IC50= 49 nM).
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Chemical Information
Name | SD-208 |
Iupac Chemical Name | 2-(5-chloro-2-fluorophenyl)-N-pyridin-4-ylpteridin-4-amine |
Synonyms | SD 208; SD208 |
Molecular Formula | C17H10ClFN6 |
Molecular Weight | 352.753 |
Smile | C1=CC(=C(C=C1Cl)C2=NC3=NC=CN=C3C(=N2)NC4=CC=NC=C4)F |
InChiKey | BERLXWPRSBJFHO-UHFFFAOYSA-N |
InChi | InChI=1S/C17H10ClFN6/c18-10-1-2-13(19)12(9-10)15-24-16-14(21-7-8-22-16)17(25-15)23-11-3-5-20-6-4-11/h1-9H,(H,20,22,23,24,25) |
CAS Number | 627536-09-8 |
Related CAS | |
Ordering Information
Packaging | Price | Availability | Purity | Shipping Time |
Bulk | | Enquiry | Enquiry | Enquiry |
Formulation | Solid powder |
Purity | 98% |
Storage | -20 ºC for 3 years |
Solubility | Soluble in DMSO |
Handling | |
Shipping Condition | Shipped under ambient temperature |
HS Code | |
Targets | |
Mechanism | |
Cell study | |
Animal study | |
Clinical study | |