SGC0946

Catalog No: 122504

CAS Number: 1561178-17-3

Purity: 98%

SGC0946 is a highly potent and selective DOT1L methyltransferase inhibitor with IC50 of 0.3 nM; selectively kill mixed lineage leukaemia cells.

For research use only. We do not sell to patients.

Name	SGC0946
Iupac Chemical Name	1-[3-[[(2R,3S,4R,5R)-5-(4-amino-5-bromopyrrolo[2,3-d]pyrimidin-7-yl)-3,4-dihydroxyoxolan-2-yl]methyl-propan-2-ylamino]propyl]-3-(4-tert-butylphenyl)urea
Synonyms	SGC-0946
Molecular Formula	C28H40BrN7O4
Molecular Weight	618.566
Smile	CC(C)N(CCCNC(=O)NC1=CC=C(C=C1)C(C)(C)C)CC2C(C(C(O2)N3C=C(C4=C3N=CN=C4N)Br)O)O
InChiKey	IQCKJUKAQJINMK-UHFFFAOYSA-N
InChi	InChI=1S/C28H40BrN7O4/c1-16(2)35(12-6-11-31-27(39)34-18-9-7-17(8-10-18)28(3,4)5)14-20-22(37)23(38)26(40-20)36-13-19(29)21-24(30)32-15-33-25(21)36/h7-10,13,15-16,20,22-23,26,37-38H,6,11-12,14H2,1-5H3,(H2,30,32,33)(H2,31,34,39)
CAS Number	1561178-17-3
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Formulation	Solid powder
Purity	98%
Storage	-20 ºC for 3 years
Solubility	Soluble in DMSO
Handling
Shipping Condition	Shipped under ambient temperature
HS Code

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