SHP394
Catalog No: 193122
CAS Number: 2055757-40-7
Purity: >98%
SHP394 is a potent and orally active SHP2 inhibitor (IC50 = 23 nM) with high lipophilic efficiency, improved potency, and enhanced pharmacokinetic properties.
For research use only. We do not sell to patients.
Chemical Information
| Name | SHP394 |
|---|---|
| Iupac Chemical Name | 6-amino-2-((3S,4S)-4-amino-3-methyl-2-oxa-8-azaspiro[4.5]decan-8-yl)-3-methyl-5-((2-(trifluoromethyl)pyridin-3-yl)thio)pyrimidin-4(3H)-one |
| Synonyms | SHP394; SHP-394; SHP 394; |
| Molecular Formula | C20H25F3N6O2S |
| Molecular Weight | 470.5152 |
| Smile | O=C1N(C)C(N(CC2)CCC32[C@H](N)[C@H](C)OC3)=NC(N)=C1SC4=CC=CN=C4C(F)(F)F |
| InChiKey | QZHZIDHAIVAHMD-SMDDNHRTSA-N |
| InChi | InChI=1S/C20H25F3N6O2S/c1-11-14(24)19(10-31-11)5-8-29(9-6-19)18-27-16(25)13(17(30)28(18)2)32-12-4-3-7-26-15(12)20(21,22)23/h3-4,7,11,14H,5-6,8-10,24-25H2,1-2H3/t11-,14+/m0/s1 |
| CAS Number | 2055757-40-7 |
| Related CAS |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | Off-white solid to white solid |
|---|---|
| Purity | >98% |
| Storage | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| Solubility | Soluble in DMSO |
| Handling | |
| Shipping Condition | Shipped under ambient temperature |
| HS Code |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
