SM-102 is an ionizable amino lipid that has been used in combination with other lipids in the formation of lipid nanoparticles. Administration of luciferase mRNA in SM-102-containing lipid nanoparticles induces hepatic luciferase expression in mice. Formulations containing SM-102 have been used in the development of lipid nanoparticles for delivery of mRNA-based vaccines.
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Name | SM-102 |
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Iupac Chemical Name | heptadecan-9-yl 8-((2-hydroxyethyl)(6-oxo-6-(undecyloxy)hexyl)amino)octanoate |
Synonyms | SM-102 ; SM102 ; SM 102 ; |
Molecular Formula | C44H87NO5 |
Molecular Weight | 710.182 |
Smile | OCCN(CCCCCC(OCCCCCCCCCCC)=O)CCCCCCCC(OC(CCCCCCCC)CCCCCCCC)=O |
InChiKey | BGNVBNJYBVCBJH-UHFFFAOYSA-N |
InChi | InChI=1S/C44H87NO5/c1-4-7-10-13-16-17-18-24-32-41-49-43(47)35-29-25-31-38-45(39-40-46)37-30-23-19-22-28-36-44(48)50-42(33-26-20-14-11-8-5-2)34-27-21-15-12-9-6-3/h42,46H,4-41H2,1-3H3 |
CAS Number | 2089251-47-6 |
Related CAS | 2089251-47-6 |
Packaging | Price | Availability | Purity | Shipping Time |
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Bulk | Enquiry | Enquiry | Enquiry |
Formulation | light-yellow liquid |
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Purity | ≧98.0% |
Storage | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
Solubility | Soluble in DMSO |
Handling | Avoid inhalation, contact with eyes and skin. Avoid dust and aerosol formation. Use only in areas with appropriate exhaust ventilation. |
Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
HS Code |
Targets | |
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Mechanism | |
Cell study | |
Animal study | |
Clinical study |