SQ22536
Catalog No: 16122726
CAS Number: 17318-31-9
Purity: 98%
SQ22536 is an inhibitor of adenylyl cyclase with an IC50 of 1.4 M. It can inhibit PGE1-stimulated increases in cAMP levels in intact human platelets.SQ22536(250 mol/L) attenuates the inhibitory effect of adenosine against ADP-induced platelet aggregation from 85 to 575%, respectively (p<0.001). SQ22536 also attenuates an increase of intraplatelet levels of cAMP by adenosine from 292 to 91 pmol/108 platelets (p<0.05). It has no effect on the platelet antiaggregant activity of inosine (1 to 4 mmol/L) and ADP-induced platelet aggregation
For research use only. We do not sell to patients.
Chemical Information
| Name | SQ22536 |
|---|---|
| Iupac Chemical Name | SQ22536 |
| Synonyms | 9-(tetrahydrofuran-2-yl)-9h-purin-6-amine |
| Molecular Formula | C9H11N5O |
| Molecular Weight | 205.22 |
| Smile | c1nc(c2c(n1)n(cn2)C3CCCO3)N |
| InChiKey | UKHMZCMKHPHFOT-UHFFFAOYSA-N |
| InChi | InChI=1S/C9H11N5O/c10-8-7-9(12-4-11-8)14(5-13-7)6-2-1-3-15-6/h4-6H,1-3H2,(H2,10,11,12) |
| CAS Number | 17318-31-9 |
| MDL | MFCD00210216 |
| Related CAS |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | crystalline solid |
|---|---|
| Purity | 98% |
| Storage | 3 years -20ºCpowder |
| Solubility | Soluble in DMSO |
| Handling | |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. |
| HS Code |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
