SR-0987 is a T cell-specific RORγ (RORγt) agonist. SR-0987 induces IL-17 expression and decreases PD-1 expression in T cells in vitro.
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Name | SR-0987 |
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Iupac Chemical Name | 2-Chloro-N-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]-benzamide |
Synonyms | SR-0987; SR0987; SR 0987 |
Molecular Formula | C16H10ClF6NO2 |
Molecular Weight | 397.7 |
Smile | O=C(NC1=CC=C(C(C(F)(F)F)(O)C(F)(F)F)C=C1)C2=CC=CC=C2Cl |
InChiKey | IZVBONMVWLTLNT-UHFFFAOYSA-N |
InChi | InChI=1S/C16H10ClF6NO2/c17-12-4-2-1-3-11(12)13(25)24-10-7-5-9(6-8-10)14(26,15(18,19)20)16(21,22)23/h1-8,26H,(H,24,25) |
CAS Number | 303126-97-8 |
Related CAS |
Packaging | Price | Availability | Purity | Shipping Time |
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Bulk | Enquiry | Enquiry | Enquiry |
Formulation | Off-white solid to white solid |
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Purity | >98% |
Storage | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
Solubility | Soluble in DMSO |
Handling | |
Shipping Condition | Shipped under ambient temperature |
HS Code |
Targets | |
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Mechanism | |
Cell study | |
Animal study | |
Clinical study |