SR 16584 is an antagonist of the α3β4 nAChR subtype (IC50 = 10.2 μM).
For research use only. We do not sell to patients.
Name | SR 16584 |
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Iupac Chemical Name | 1-((1R,3s,5S)-9-methyl-9-azabicyclo[3.3.1]nonan-3-yl)indolin-2-one |
Synonyms | SR 16584; SR-16584; SR16584 |
Molecular Formula | C17H22N2O |
Molecular Weight | 270.37 |
Smile | O=C(CC1=C2C=CC=C1)N2[C@@H]3C[C@H](N4C)CCC[C@H]4C3 |
InChiKey | GIDZCNCCCWFCIN-QDMKHBRRSA-N |
InChi | InChI=1S/C17H22N2O/c1-18-13-6-4-7-14(18)11-15(10-13)19-16-8-3-2-5-12(16)9-17(19)20/h2-3,5,8,13-15H,4,6-7,9-11H2,1H3/t13-,14+,15- |
CAS Number | 1150153-86-8 |
Related CAS |
Packaging | Price | Availability | Purity | Shipping Time |
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Formulation | Off-white solid |
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Purity | 98% Min. |
Storage | Dry, dark and at 0 - 4℃ for short term (days to weeks) or -20℃ for long term (months to years). |
Solubility | Soluble in DMSO |
Handling | |
Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
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Clinical study |
Frara N, Barbe MF, Giaddui D, Porreca DS, Braverman AS, Tiwari E, Ahmad A, Brown JM, Johnston BR, Bazarek SF, Ruggieri MR Sr. Nerve transfer for restoration of lower motor neuron-lesioned bladder, urethral, and anal sphincter function in a dog model. Part 3. nicotinic receptor characterization. Am J Physiol Regul Integr Comp Physiol. 2023 Oct 1;325(4):R344-R358. doi: 10.1152/ajpregu.00273.2022. Epub 2023 Jul 17. PMID: 37458380; PMCID: PMC10642361.