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SR 16584

Catalog No: 24137
CAS Number: 1150153-86-8
Purity: 98% Min.

SR 16584 is an antagonist of the α3β4 nAChR subtype (IC50 = 10.2 μM).

For research use only. We do not sell to patients.

Chemical Information

NameSR 16584
Iupac Chemical Name1-((1R,3s,5S)-9-methyl-9-azabicyclo[3.3.1]nonan-3-yl)indolin-2-one
SynonymsSR 16584; SR-16584; SR16584
Molecular FormulaC17H22N2O
Molecular Weight270.37
SmileO=C(CC1=C2C=CC=C1)N2[C@@H]3C[C@H](N4C)CCC[C@H]4C3
InChiKeyGIDZCNCCCWFCIN-QDMKHBRRSA-N
InChiInChI=1S/C17H22N2O/c1-18-13-6-4-7-14(18)11-15(10-13)19-16-8-3-2-5-12(16)9-17(19)20/h2-3,5,8,13-15H,4,6-7,9-11H2,1H3/t13-,14+,15-
CAS Number1150153-86-8
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Ordering Information

PackagingPriceAvailabilityPurityShipping Time
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FormulationOff-white solid
Purity98% Min.
StorageDry, dark and at 0 - 4℃ for short term (days to weeks) or -20℃ for long term (months to years).
SolubilitySoluble in DMSO
Handling
Shipping ConditionShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
HS Code
Coming soon.
Targets
Mechanism
Cell study
Animal study
Clinical study

Frara N, Barbe MF, Giaddui D, Porreca DS, Braverman AS, Tiwari E, Ahmad A, Brown JM, Johnston BR, Bazarek SF, Ruggieri MR Sr. Nerve transfer for restoration of lower motor neuron-lesioned bladder, urethral, and anal sphincter function in a dog model. Part 3. nicotinic receptor characterization. Am J Physiol Regul Integr Comp Physiol. 2023 Oct 1;325(4):R344-R358. doi: 10.1152/ajpregu.00273.2022. Epub 2023 Jul 17. PMID: 37458380; PMCID: PMC10642361.

Chemical Structure

24137 - SR 16584 | CAS 1150153-86-8

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