STA-21
Catalog No: 16122706
CAS Number: 111540-00-2
Purity: 98%
STA-21 is a selective STAT3 inhibitor.In cells, STA-21 inhibits Stat3 DNA binding activity, Stat3 dimerization, and Stat3-dependent luciferase activity. STA-21 remarkably inhibits the growth and the survival of the breast carcinoma cells MDA-MB-231, MDA-MB-435s, and MDA-MB-468 that express persistently activated Stat3. [1] In RH30 and RD2 cells, STA-21 also inhibits cell viability and growth and induced apoptosis through caspases 3, 8 and 9 pathways.
For research use only. We do not sell to patients.
Chemical Information
| Name | STA-21 |
|---|---|
| Iupac Chemical Name | STA-21 |
| Synonyms | N/A |
| Molecular Formula | C19H14O4 |
| Molecular Weight | 306.31 |
| Smile | C[C@H]1Cc2ccc3c(c2C(=O)C1)C(=O)c4cccc(c4C3=O)O |
| InChiKey | ZAWXOCUFQSQDJS-VIFPVBQESA-N |
| InChi | InChI=1S/C19H14O4/c1-9-7-10-5-6-12-17(15(10)14(21)8-9)19(23)11-3-2-4-13(20)16(11)18(12)22/h2-6,9,20H,7-8H2,1H3/t9-/m0/s1 |
| CAS Number | 111540-00-2 |
| MDL | MFCD09802288 |
| Related CAS |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | crystalline solid |
|---|---|
| Purity | 98% |
| Storage | 3 years -20ºCpowder |
| Solubility | Soluble in DMSO |
| Handling | |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. |
| HS Code |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
