STX-478 is a second generation, mutant-selective, oral PI3Ka small molecule allosteric inhibitor.
For research use only. We do not sell to patients.
Name | STX-478 |
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Iupac Chemical Name | (R)-1-(2-aminopyrimidin-5-yl)-3-(1-(5,7-difluoro-3-methylbenzofuran-2-yl)-2,2,2-trifluoroethyl)urea |
Synonyms | STX-478 ; STX 478 ; STX478 ; |
Molecular Formula | C16H12F5N5O2 |
Molecular Weight | 401.29 |
Smile | O=C(N[C@H](C1=C(C)C2=CC(F)=CC(F)=C2O1)C(F)(F)F)NC3=CN=C(N)N=C3 |
InChiKey | LGPNQALKGDDVBD-CYBMUJFWSA-N |
InChi | InChI=1S/C16H12F5N5O2/c1-6-9-2-7(17)3-10(18)12(9)28-11(6)13(16(19,20)21)26-15(27)25-8-4-23-14(22)24-5-8/h2-5,13H,1H3,(H2,22,23,24)(H2,25,26,27)/t13-/m1/s1 |
CAS Number | 2883540-92-7 |
Related CAS | 2883540-92-7 |
Packaging | Price | Availability | Purity | Shipping Time |
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Bulk | Enquiry | Enquiry | Enquiry |
Formulation | Off-white solid |
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Purity | ≧98.0% |
Storage | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
Solubility | Soluble in DMSO |
Handling | Refer to MSDS |
Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
HS Code | 2934200090 |
Targets | PI3Kα inhibitor |
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Mechanism | |
Cell study | |
Animal study | |
Clinical study |