Segetalin B
Segetalin B is natural product isolated from Seeds of Vaccaria Segetalis. Segetalin B demonstrated to have an estrogen-like activity.
For research use only. We do not sell to patients.
Chemical Information
| Name | Segetalin B |
|---|---|
| Iupac Chemical Name | (3S,6S,9S,12S)-6-(1H-indol-3-ylmethyl)-12-isopropyl-3,9-dimethyl-1,4,7,10,13pentaaza-cyclopentadecane-2,5,8,11,14-pentaone |
| Synonyms | Segetalin B; Vaccarin A, Segetalin B, Segetaline B; Cyclo(L-alanylglycyl-L-valyl-L-alanyl-L-tryptophyl) |
| Molecular Formula | C24H32N6O5 |
| Molecular Weight | 484.557 |
| Smile | O=C([C@H](C)NC([C@H](CC1=CNC2=C1C=CC=C2)NC([C@H](C)NC([C@H](C(C)C)N3)=O)=O)=O)NCC3=O |
| InChiKey | VBQDUSUKSGAFMN-OACKDKIBSA-N |
| InChi | InChI=1S/C24H32N6O5/c1-12(2)20-24(35)28-14(4)22(33)29-18(9-15-10-25-17-8-6-5-7-16(15)17)23(34)27-13(3)21(32)26-11-19(31)30-20/h5-8,10,12-14,18,20,25H,9,11H2,1-4H3,(H,26,32)(H,27,34)(H,28,35)(H,29,33)(H,30,31)/t13-,14-,18-,20-/m0/s1 |
| CAS Number | 164991-89-3 |
| Related CAS |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | Solid powder |
|---|---|
| Purity | 98% Min. |
| Storage | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). Solubility:Soluble in DMSO |
| Solubility | Soluble in DMSO |
| Handling | |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| HS Code |
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
1: Wang X, Dong H, Liu Y, Yang B, Wang X, Huang L. Application of high-speed counter-current chromatography for preparative separation of cyclic peptides from Vaccaria segetalis. J Chromatogr B Analyt Technol Biomed Life Sci. 2011 Apr 1;879(11-12):811-4. doi: 10.1016/j.jchromb.2011.02.001. PMID: 21396894.
2: Morita H, Yun YS, Takeya K, Itokawa H, Shirota O. Thionation of segetalins A and B, cyclic peptides with estrogen-like activity from seeds of Vaccaria segetalis. Bioorg Med Chem. 1997 Mar;5(3):631-6. doi: 10.1016/s0968-0896(97)00001-1. PMID: 9113340.
3: Itokawa H, Yun Y, Morita H, Takeya K, Yamada K. Estrogen-like activity of cyclic peptides from Vaccaria segetalis extracts. Planta Med. 1995 Dec;61(6):561-2. doi: 10.1055/s-2006-959373. PMID: 8824953.
Chemical Structure
