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Selonsertib(GS-4997)

Catalog No: 100503
CAS Number: 1448428-04-3
Purity: 98% by HPLC/HNMR 

Selonsertib is a apoptosis signal-regulating kinase inhibitor (ASK1). Selonsertib may be potential useful in the treatment of ASK1-mediated conditions, including autoimmune disorders, inflammatory diseases, cardiovascular diseases and neurodegenerative diseases. 

For research use only. We do not sell to patients.

Chemical Information

NameSelonsertib(GS-4997)
Iupac Chemical Name5-(4-cyclopropyl-1H-imidazol-1-yl)-2-fluoro-N-(6-(4-isopropyl-4H-1,2,4-triazol-3-yl)pyridin-2-yl)-4-methylbenzamide 
SynonymsGS-4997; GS4997; GS 4997; Selonsertib free base 
Molecular FormulaC24H24FN7O 
Molecular Weight445.49 
SmileO=C(NC1=NC(C2=NN=CN2C(C)C)=CC=C1)C3=CC(N4C=C(C5CC5)N=C4)=C(C)C=C3F
InChiKeyYIDDLAAKOYYGJG-UHFFFAOYSA-N
InChiInChI=1S/C24H24FN7O/c1-14(2)32-13-27-30-23(32)19-5-4-6-22(28-19)29-24(33)17-10-21(15(3)9-18(17)25)31-11-20(26-12-31)16-7-8-16/h4-6,9-14,16H,7-8H2,1-3H3,(H,28,29,33)
CAS Number1448428-04-3
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Ordering Information

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Formulationoff-white solid to white solid 
Purity98% by HPLC/HNMR 
Storage3 years -20ºCpowder 6 months-80ºCin solvent 
SolubilitySoluble in DMSO 
Handling
Shipping ConditionShipped under ambient temperature 
HS Code
Coming soon.
Targets
Mechanism
Cell study
Animal study
Clinical study
Not available

Chemical Structure

100503 - Selonsertib(GS-4997) | CAS 1448428-04-3

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