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Sitravatinib (MGCD516)

Catalog No: 178906
CAS Number: 1123837-84-2
Purity: 98% by HPLC/HNMR

Sitravatinib, also known as MGCD516 or MG516, is a novel small molecule inhibitor targeting multiple RTKs involved in driving sarcoma cell growth.

For research use only. We do not sell to patients.

Chemical Information

NameSitravatinib (MGCD516)
Iupac Chemical NameN-(3-fluoro-4-((2-(5-(((2-methoxyethyl)amino)methyl)pyridin-2-yl)thieno[3,2-b]pyridin-7-yl)oxy)phenyl)-N-phenylcyclopropane-1,1-dicarboxamide
SynonymsMGCD516;MGCD-516;MGCD 516;MG516;MG 516;MG-516;Sitravatinib
Molecular FormulaC33H29F2N5O4S
Molecular Weight629.68
SmileFC=1C=C(C=CC1OC1=C2C(=NC=C1)C=C(S2)C2=NC=C(C=C2)CNCCOC)N(C(=O)C2(CC2)C(=O)N)C2=CC=CC=C2
InChiKeyIAEHJPSRIPKAAJ-UHFFFAOYSA-N
InChiInChI=1S/C33H30FN5O4S/c1-42-16-15-36-19-21-7-9-25(38-20-21)29-18-26-30(44-29)28(11-14-37-26)43-27-10-8-23(17-24(27)34)39(22-5-3-2-4-6-22)32(41)33(12-13-33)31(35)40/h2-11,14,17-18,20,36H,12-13,15-16,19H2,1H3,(H2,35,40)
CAS Number1123837-84-2
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Ordering Information

PackagingPriceAvailabilityPurityShipping Time
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Formulationcrystalline solid
Purity98% by HPLC/HNMR
Storage3 years -20℃powder 6 months-80℃in solvent
SolubilitySoluble in DMSO
Handling
Shipping ConditionShipped under ambient temperature.
HS Code
Coming soon.
Targets
Mechanism
Cell study
Animal study
Clinical study
Not available

Chemical Structure

178906 - Sitravatinib (MGCD516) | CAS 1123837-84-2

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