TAS-103, also known as BMS-247615, is a quinoline derivative that displays antitumor activity in murine and human tumor models, which has been reported to be a potent topoisomerase II poison.
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Chemical Information
Name TAS-103 dihydrochloride
Iupac Chemical Name 6-((2-(dimethylamino)ethyl)amino)-3-hydroxy-7H-indeno[2,1-c]quinolin-7-one dihydrochloride
Synonyms TAS103; TAS 103; BMS-247615; BMS 247615; BMS247615
Molecular Formula C20H21Cl2N3O2
Molecular Weight 406.31
Smile Cl.Cl.CN(CCNC1=NC2=CC(=CC=C2C2=C1C(C1=CC=CC=C12)=O)O)C
InChiKey HAYAYGFVSIWSGQ-UHFFFAOYSA-N
InChi InChI=1S/C20H19N3O2.2ClH/c1-23(2)10-9-21-20-18-17(13-5-3-4-6-14(13)19(18)25)15-8-7-12(24)11-16(15)22-20;;/h3-8,11,24H,9-10H2,1-2H3,(H,21,22);2*1H
CAS Number 174634-09-4
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Ordering Information
Packaging Price Availability Purity Shipping Time
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Formulation Solid powder
Purity 98%
Storage -20 ºC for 3 years
Solubility Soluble in DMSO
Handling
Shipping Condition Shipped under ambient temperature
HS Code
Targets
Mechanism
Cell study
Animal study
Clinical study