TAS-109, also known as DFP-10917 and CNDAC, is an analogue of the nucleoside deoxycytidine with potential antineoplastic activity. Nucleoside analogue TAS-109 is incorporated into DNA and directly inhibits the activity of DNA polymerase, which may result in inhibition of DNA replication and cell cycle arrest in the S and G2/M phases, DNA fragmentation, and tumor cell apoptosis.
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Chemical Information
Name
TAS-109
Iupac Chemical Name
TAS-109
Synonyms
TAS109; TAS109; TAS 109; DFP-10917; DFP 10917; DFP10917. CNDAC