SB1317 (TG02) is a novel small molecule potent CDK/JAK2/FLT3 inhibitor. SB1317 was soluble, highly permeable in Caco-2 cells, and showed > 99% binding to plasma from mice, dog and humans.
For research use only. We do not sell to patients.
Name | TG02 ( SB1317 ) |
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Iupac Chemical Name | 14-Methyl-20-oxa-5,7,14,27-tetraazatetracyclo[19.3.1.12,6.18,12]heptacosa-1(25),2,4,6(27),8,10,12(26),16,21,23-decaene |
Synonyms | TG-02 ; TG 02 ; TG02 ; SB1317; SB-1317 ; SB 1317 |
Molecular Formula | C23H24N4O |
Molecular Weight | 372.46 |
Smile | CN1CC=2C=CC=C(NC=3N=CC=C(C=4C=CC=C(OCCC=CC1)C4)N3)C2 |
InChiKey | VXBAJLGYBMTJCY-UHFFFAOYSA-N |
InChi | InChI=1S/C23H24N4O/c1-27-13-3-2-4-14-28-21-10-6-8-19(16-21)22-11-12-24-23(26-22)25-20-9-5-7-18(15-20)17-27/h2-3,5-12,15-16H,4,13-14,17H2,1H3,(H,24,25,26) |
CAS Number | 937270-47-8 |
Related CAS | 937270-47-8 |
Packaging | Price | Availability | Purity | Shipping Time |
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Bulk | Enquiry | Enquiry | Enquiry |
Formulation | Off-white solid to white solid |
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Purity | ≧98.0% |
Storage | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
Solubility | Soluble in DMSO |
Handling | Avoid inhalation, contact with eyes and skin. Avoid dust and aerosol formation. Use only in areas with appropriate exhaust ventilation. |
Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. |
HS Code |
Targets | CDK/JAK2/FLT3 inhibitor |
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Mechanism | |
Cell study | |
Animal study | |
Clinical study |