TH287 is a potent inhibitor of human 7,8-Dihydro-8-oxoguaninetriphosphatase MTH1 (NUDT1) with an IC50 value of 5 nM and good metabolic stability.
For research use only. We do not sell to patients.
Name | TH287 |
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Iupac Chemical Name | 6-(2,3-dichlorophenyl)-N4-methylpyrimidine-2,4-diamine |
Synonyms | TH287; TH 287; TH-287. |
Molecular Formula | C11H10Cl2N4 |
Molecular Weight | 269.13 |
Smile | NC1=NC(C2=CC=CC(Cl)=C2Cl)=CC(NC)=N1 |
InChiKey | URWCXPXBBITYLR-UHFFFAOYSA-N |
InChi | InChI=1S/C11H10Cl2N4/c1-15-9-5-8(16-11(14)17-9)6-3-2-4-7(12)10(6)13/h2-5H,1H3,(H3,14,15,16,17) |
CAS Number | 1609960-30-6 |
Related CAS |
Packaging | Price | Availability | Purity | Shipping Time |
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Bulk | Enquiry | Enquiry | Enquiry |
Formulation | Off-white solid to white solid |
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Purity | >98% |
Storage | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
Solubility | Soluble in DMSO |
Handling | |
Shipping Condition | Shipped under ambient temperature |
HS Code |
Targets | |
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Mechanism | |
Cell study | |
Animal study | |
Clinical study |