TP0463518

Catalog No: 1812282

CAS Number: 1558021-37-0

Purity: >98%

TP0463518 is a novel, highly potent HIF prolyl hydroxylase (PHD) inhibitor. TP0463518 competitively inhibited human PHD2 with a Ki value of 5.3 nM.

For research use only. We do not sell to patients.

Name	TP0463518
Iupac Chemical Name	(1-((6-(4-chlorophenoxy)pyridin-3-yl)methyl)-4-hydroxy-2-oxo-1,2,5,6-tetrahydropyridine-3-carbonyl)glycine
Synonyms	TP0463518; TP-0463518; TP 0463518;
Molecular Formula	C20H18ClN3O6
Molecular Weight	431.829
Smile	O=C(O)CNC(C1=C(O)CCN(CC2=CC=C(OC3=CC=C(Cl)C=C3)N=C2)C1=O)=O
InChiKey	HMMHKGLPKAQOOH-UHFFFAOYSA-N
InChi	InChI=1S/C20H18ClN3O6/c21-13-2-4-14(5-3-13)30-16-6-1-12(9-22-16)11-24-8-7-15(25)18(20(24)29)19(28)23-10-17(26)27/h1-6,9,25H,7-8,10-11H2,(H,23,28)(H,26,27)
CAS Number	1558021-37-0
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Formulation	Off-white solid to white solid
Purity	>98%
Storage	Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility	Soluble in DMSO
Handling
Shipping Condition	Shipped under ambient temperature
HS Code

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