Takinib is a selective TAK1 inhibitor that induces apoptosis following TNF-α stimulation in cell models of rheumatoid arthritis and metastatic breast cancer.
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Name | Takinib |
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Iupac Chemical Name | 3-N-(1-Propylbenzimidazol-2-yl)benzene-1,3-dicarboxamide |
Synonyms | Takinib; EDHS-206; EDHS 206; EDHS206; |
Molecular Formula | C18H18N4O2 |
Molecular Weight | 322.36 |
Smile | O=C(C1=CC=CC(C(NC2=NC3=CC=CC=C3N2CCC)=O)=C1)N |
InChiKey | UOZVVPXKJGOFIG-UHFFFAOYSA-N |
InChi | InChI=1S/C18H18N4O2/c1-2-10-22-15-9-4-3-8-14(15)20-18(22)21-17(24)13-7-5-6-12(11-13)16(19)23/h3-9,11H,2,10H2,1H3,(H2,19,23)(H,20,21,24) |
CAS Number | 1111556-37-6 |
Related CAS |
Packaging | Price | Availability | Purity | Shipping Time |
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Bulk | Enquiry | Enquiry | Enquiry |
Formulation | Off-white solid to white solid |
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Purity | >98% |
Storage | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
Solubility | Soluble in DMSO |
Handling | |
Shipping Condition | Shipped under ambient temperature |
HS Code |
Targets | |
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Mechanism | |
Cell study | |
Animal study | |
Clinical study |