Telatinib is a potent inhibitor of VEGFR2/3, c-Kit and PDGFR with IC50 of 6 nM/4 nM, 1 nM and 15 nM, respectively.
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Chemical Information
Name | Telatinib |
Iupac Chemical Name | 4-[[4-(4-chloroanilino)furo[2,3-d]pyridazin-7-yl]oxymethyl]-N-methylpyridine-2-carboxamide |
Synonyms | Bay 57-9352 |
Molecular Formula | C20H16ClN5O3 |
Molecular Weight | 409.826 |
Smile | CNC(=O)C1=NC=CC(=C1)COC2=NN=C(C3=C2OC=C3)NC4=CC=C(C=C4)Cl |
InChiKey | QFCXANHHBCGMAS-UHFFFAOYSA-N |
InChi | InChI=1S/C20H16ClN5O3/c1-22-19(27)16-10-12(6-8-23-16)11-29-20-17-15(7-9-28-17)18(25-26-20)24-14-4-2-13(21)3-5-14/h2-10H,11H2,1H3,(H,22,27)(H,24,25) |
CAS Number | 332012-40-5 |
Related CAS | |
Ordering Information
Packaging | Price | Availability | Purity | Shipping Time |
Bulk | | Enquiry | Enquiry | Enquiry |
Formulation | Solid powder |
Purity | 98% |
Storage | -20 ºC for 3 years |
Solubility | Soluble in DMSO |
Handling | |
Shipping Condition | Shipped under ambient temperature |
HS Code | |
Targets | |
Mechanism | |
Cell study | |
Animal study | |
Clinical study | |