Teniposide
Catalog No: 17011723
CAS Number: 29767-20-2
Purity: 98%
Teniposide is a semisynthetic derivative of podophyllotoxin with antineoplastic activity. Teniposide forms a ternary complex with the enzyme topoisomerase II and DNA, resulting in dose-dependent single- and double-stranded breaks in DNA, DNA: protein cross-links, inhibition of DNA strand religation, and cytotoxicity. This agent acts in the late S or early G phase of the cell cycle.
For research use only. We do not sell to patients.
Chemical Information
| Name | Teniposide |
|---|---|
| Iupac Chemical Name | (5S,5aR,8aR,9S)-9-(((2R,4aR,6R,7R,8R,8aS)-7,8-dihydroxy-2-(thiophen-2-yl)hexahydropyrano[3,2-d][1,3]dioxin-6-yl)oxy)-5-(4-hydroxy-3,5-dimethoxyphenyl)-5,5a,8a,9-tetrahydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxol-6(8H)-one |
| Synonyms | NSC-122819; NSC 122819; NSC122819; VM26; VM-26; VM 26; HSDB 6546; HSDB6546; HSDB-6546; CCRIS 2058. Brand name: Vumon; Vehem. Abbreviations: EPT; PTG |
| Molecular Formula | C32H32O13S |
| Molecular Weight | 656.65 |
| Smile | O[C@@H]1[C@H]([C@@H]2O[C@@H](OC[C@H]2O[C@H]1O[C@H]1[C@@H]2[C@@H]([C@H](C3=CC4=C(OCO4)C=C13)C1=CC(=C(C(=C1)OC)O)OC)C(OC2)=O)C=2SC=CC2)O |
| InChiKey | NRUKOCRGYNPUPR-DKQCQWADSA-N |
| InChi | InChI=1S/C32H32O13S/c1-37-19-6-13(7-20(38-2)25(19)33)23-14-8-17-18(42-12-41-17)9-15(14)28(16-10-39-30(36)24(16)23)44-32-27(35)26(34)29-21(43-32)11-40-31(45-29)22-4-3-5-46-22/h3-9,16,21,23-24,26-29,31-35H,10-12H2,1-2H3/t16-,21+,23-,24-,26+,27+,28+,29+,31+,32-/m0/s1 |
| CAS Number | 29767-20-2 |
| Related CAS |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | crystalline solid |
|---|---|
| Purity | 98% |
| Storage | 3 years -20ºCpowder |
| Solubility | Soluble in DMSO |
| Handling | |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. |
| HS Code |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
