Thiotepa is a polyfunctional, organophosphorus alkylating agent and a stable derivative of N,N',N''-triethylenephosphoramide (TEPA), with antineoplastic activity.
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Chemical Information
Name Thiotepa
Iupac Chemical Name tri(aziridin-1-yl)phosphine sulfide
Synonyms AI3 24916; AI324916; AI3-24916; NSC-6396; NSC 6396; NSC6396; Girostan; thiophosphamide; thiophosphoramide; triethylene thiophosphoramide. US brand names: Girostan; STEPA; TESPA; Thiofozil; Thioplex; Tifosyl. Foreign brand names: Ledertepa; Onco Tiotepa; Oncotiotepa; Tespamin; Tespamine; Thiotef; TioTEF; Abbreviation: TSPA. Code name: WR 45312; WR45312; WR45312
Molecular Formula C6H12N3PS
Molecular Weight 189.22
Smile N1(CC1)P(N1CC1)(N1CC1)=S
InChiKey FOCVUCIESVLUNU-UHFFFAOYSA-N
InChi InChI=1S/C6H12N3PS/c11-10(7-1-2-7,8-3-4-8)9-5-6-9/h1-6H2
CAS Number 52-24-4
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Ordering Information
Packaging Price Availability Purity Shipping Time
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Formulation off-white solid
Purity 98%
Storage 3 years -20ºCpowder
Solubility Soluble in DMSO
Handling
Shipping Condition Shipped under ambient temperature as non-hazardous chemical.
HS Code
Targets
Mechanism
Cell study
Animal study
Clinical study