Tideglusib protects neural stem cells against NMDA receptor overactivation. Tideglusib reduces progression of brain atrophy in progressive supranuclear palsy in a randomized trial. Tideglusib prevents inflammation and neurodegeneration under excitotoxic conditions: potential therapeutic role in brain disorders.
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Name | Tideglusib |
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Iupac Chemical Name | 2-(1-naphthalenyl)-4-(phenylmethyl)-1,2,4-thiadiazolidine-3,5-dione |
Synonyms | NP031112; NP 031112; NP-031112; Tideglusib. |
Molecular Formula | C19H14N2O2S |
Molecular Weight | 334.393 |
Smile | C1(=CC=CC2=CC=CC=C12)N1SC(N(C1=O)CC1=CC=CC=C1)=O |
InChiKey | PMJIHLSCWIDGMD-UHFFFAOYSA-N |
InChi | InChI=1S/C19H14N2O2S/c22-18-20(13-14-7-2-1-3-8-14)19(23)24-21(18)17-12-6-10-15-9-4-5-11-16(15)17/h1-12H,13H2 |
CAS Number | 865854-05-3 |
Related CAS |
Packaging | Price | Availability | Purity | Shipping Time |
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Bulk | Enquiry | Enquiry | Enquiry |
Formulation | Solid powder |
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Purity | 98% |
Storage | -20 ºC for 3 years |
Solubility | Soluble in DMSO |
Handling | |
Shipping Condition | Shipped under ambient temperature |
HS Code |
Targets | |
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Mechanism | |
Cell study | |
Animal study | |
Clinical study |