Timapiprant,又名OC000459,是一种强效、选择性和口服的CRTH2拮抗剂。OC000459减少了对花粉过敏的受试者的鼻和眼症状,这是一种随机、安慰剂对照、双盲试验。
For research use only. We do not sell to patients.
Name | Timapiprant |
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Iupac Chemical Name | 2-(5-fluoro-2-methyl-3-(quinolin-2-ylmethyl)-1H-indol-1-yl)acetic acid |
Synonyms | OC000459; OC-000459; OC 000459; Timapiprant. |
Molecular Formula | C21H17FN2O2 |
Molecular Weight | 348.3774 |
Smile | O=C(O)CN1C(C)=C(CC2=NC3=CC=CC=C3C=C2)C4=C1C=CC(F)=C4 |
InChiKey | FATGTHLOZSXOBC-UHFFFAOYSA-N |
InChi | InChI=1S/C21H17FN2O2/c1-13-17(11-16-8-6-14-4-2-3-5-19(14)23-16)18-10-15(22)7-9-20(18)24(13)12-21(25)26/h2-10H,11-12H2,1H3,(H,25,26) |
CAS Number | 851723-84-7 |
Related CAS |
Packaging | Price | Availability | Purity | Shipping Time |
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Bulk | Enquiry | Enquiry | Enquiry |
Formulation | 白色粉末 |
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Purity | >98% |
Storage | 短期可在0-4度保存,数天至数月;长期可在-20度保存三年。 |
Solubility | 可溶于DMSO |
Handling | |
Shipping Condition | 可在常温下运输 |
HS Code |
Targets | |
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Mechanism | |
Cell study | |
Animal study | |
Clinical study |