Tipiracil HCl
Catalog No: 17030710
CAS Number: 183204-72-0
Purity: 98%
Tipiralacil, also known as TPI, is a thymidine phosphorylase inhibitor (TPI). Tipiracil is one of the active components in TAS-102, which is an anticancer drug candidate currently in clinical trials. TAS-102 consists of the cytotoxin Trifluridine and the thymidine phosphorylase inhibitor (TPI) tipiracil. Trifluridine is incorporated into DNA during DNA synthesis and inhibits tumor cell growth. Tipiracil protects trifluridine from being broken down when taken orally. TAS-102 was approved in Japan in 2015.
For research use only. We do not sell to patients.
Chemical Information
| Name | Tipiracil HCl |
|---|---|
| Iupac Chemical Name | 5-chloro-6-((2-iminopyrrolidin-1-yl)methyl)pyrimidine-2,4(1H,3H)-dione hydrochloride |
| Synonyms | TAS-1-462, MA-1; Tipiracil HCl, TPI; TAS-102 |
| Molecular Formula | C9H12Cl2N4O2 |
| Molecular Weight | 279.12318 |
| Smile | Cl.ClC=1C(NC(NC1CN1C(CCC1)=N)=O)=O |
| InChiKey | KGHYQYACJRXCAT-UHFFFAOYSA-N |
| InChi | InChI=1S/C9H11ClN4O2.ClH/c10-7-5(12-9(16)13-8(7)15)4-14-3-1-2-6(14)11;/h11H,1-4H2,(H2,12,13,15,16);1H |
| CAS Number | 183204-72-0 |
| Related CAS |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | off-white solid |
|---|---|
| Purity | 98% |
| Storage | 3 years -20ºCpowder |
| Solubility | Soluble in DMSO |
| Handling | |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. |
| HS Code |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
