Tolebrutinib, also known as SAR442168, is a Bruton tyrosine kinase inhibitor.
For research use only. We do not sell to patients.
Name | Tolebrutinib |
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Iupac Chemical Name | 4-amino-3-(4-phenoxyphenyl)-1-[(3R)-1-(prop-2-enoyl)piperidin-3-yl]-1,3-dihydro-2H-imidazo[4,5-c]pyridin-2-one |
Synonyms | Tolebrutinib; SAR442168; SAR-442168; SAR 442168; |
Molecular Formula | C26H25N5O3 |
Molecular Weight | 455.518 |
Smile | O=C(N1[C@H]2CN(C(C=C)=O)CCC2)N(C3=CC=C(OC4=CC=CC=C4)C=C3)C5=C1C=CN=C5N |
InChiKey | KOEUOFPEZFUWRF-LJQANCHMSA-N |
InChi | InChI=1S/C26H25N5O3/c1-2-23(32)29-16-6-7-19(17-29)30-22-14-15-28-25(27)24(22)31(26(30)33)18-10-12-21(13-11-18)34-20-8-4-3-5-9-20/h2-5,8-15,19H,1,6-7,16-17H2,(H2,27,28)/t19-/m1/s1 |
CAS Number | 1971920-73-6 |
Related CAS |
Packaging | Price | Availability | Purity | Shipping Time |
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Bulk | Enquiry | Enquiry | Enquiry |
Formulation | Solid powder |
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Purity | 98% Min. |
Storage | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
Solubility | Soluble in DMSO |
Handling | |
Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
HS Code |
Targets | |
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Mechanism | |
Cell study | |
Animal study | |
Clinical study |